Pathological Fractures in Primary Non-Hodgkin’s Lymphoma of the Bone: A Case Series with Review of the Literature
Published: March 1, 2013 | DOI: https://doi.org/10.7860/JCDR/2013/.2809
Yasir Salam Siddiqui, Abdul Qayyum Khan, MKA Sherwani
1. Assistant Professor, Department of Orthopaedic Surgery,
JN Medical College, AMU, Aligarh, India.
2. Assistant Professor, Department of Orthopaedic Surgery,
JN Medical College, AMU, Aligarh. India.
3. Professor, Department of Orthopaedic Surgery,
JN Medical College, AMU, Aligarh, India.
Correspondence
Dr. Yasir Salam Siddiqui,
Assistant Professor, Department of Orthopaedic Surgery
Jawaharlal Nehru Medical College,
Aligarh Muslim University, Aligarh, India.
Phone: +919837343400
E-mail: yassu98@gmail.com
Primary non-Hodgkin’s lymphoma of bone (PLB) is a rare entity. Patients generally present with localized bone pain and, less frequently, soft-tissue swelling or a palpable mass. Pathological fracture of the proximal femur and proximal humerus secondary to soft-tissue tumours is well documented in the literature; however, lymphomas presenting primarily at these sites with pathological fracture is unusual. A review of the world literature shows that the incidence of skeletal manifestation from NHL is less than 5%, and in all these cases, bony involvement was reported many years after presentation of the primary cancer. Histopathologically, PLB usually represents diffuse large B-cell lymphoma. We report our experience with two cases of Primary non-Hodgkin’s lymphoma of proximal femur and proximal humerus with pathological fracture and their management.
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